An Alpha-2-Macroglobulin (A2M) injection is a cutting-edge, non-surgical treatment for osteoarthritis and joint pain. A2M is a naturally occurring protein found in blood plasma, known for its powerful ability to inhibit cartilage breakdown and neutralize inflammatory enzymes. By isolating and concentrating A2M from a patient’s blood sample, we create a personalized therapeutic injection.Â
When administered directly into the affected joint, this injection can halt the progression of joint degeneration and reduces inflammation, providing relief from pain and improving overall joint function. A2M injections offer an alternative to more invasive surgical procedures for those suffering from osteoarthritis.Â
HEALTHY AGING PREVENTATIVE BIOLOGICS: A2M INJECTION
The A2M injection can be administered as a preventative injection for patents who are suffering from osteoarthritis or have signs of osteoarthritis. It can inhibit cartilage breakdown and reduce inflammation providing a natural powerful alternative to invasive procedures or medication .
INHIBITING CARTILAGE BREAKDOWN WITH AN A2M INJECTION
The A2M injection is a simple in office procedure. Blood is drawn from the patient and then processed in a centrifuge. After spinning, the separated plasma goes through and additional filtration process to isolate the A2M.Â
An A2M injection contains a dose of the A2M molecule that is approximately 6X more concentrated than what already occurs in your body naturally. This concentrated A2M is then injected back into the problem joint or joints where it attaches to and removes destructive enzymes, called proteases. These proteases damage the cartilage cells and tissues and cause osteoarthritis in the joint or disc space.
So A2M injections may effectively halt the destruction of cartilage seen and felt in Osteoarthritis.
Patients generally feel no inflammation or pain after the injection. More importantly they often note improved pain and mobility in the injected joint. The time frame of relief can vary based on age, severity of osteoarthritis, and several other factors.Â
the breakdown of cartilage and shut down destructive inflammatory proteins in the joint
the arthritis which often occurs after ligament damage
the development of post-traumatic osteoarthritis
An A2M Injection may have significant benefits compared to other osteoarthritis treatments such as steroid injections and medications. Other treatments help symptoms temporarily while A2M injections can help rejuvenate, repair, and heal damaged tissue and cartilage.Â
A2M may prevent or remove the root cause of the painful swelling and inflammation, and contains growth factors as well as other regenerative factors that aid in the restoration and rejuvenation of the joint – making A2M a more permanent solution to osteoarthritis.
A2M inhibits the actions of certain types of proteinases. Proteinases are enzymes that break down proteins. A2M inhibits certain of these proteinase types that degrade the collagen within cartilage, effectively neutralizing the process that leads to osteoarthritic cartilage degradation and joint destruction. By inhibiting these proteins, A2M may inhibit or prevent the breakdown of joint cartilage.
Your liver actually makes large quantities of Alpha-2-Macroglobulin and it circulates in your blood stream in reasonably high quantities. Unfortunately, studies have shown that the A2M molecule is just too big to cross over into your joint or back in sufficient quantities to effectively neutralize those destructive proteins that are destroying your joint. That’s where we can help by extracting, concentrating and injecting the A2M where it’s needed.
There are many research studies show that cellular therapy and platelet rich plasma injections may provide excellent relief from joint and musculoskeletal pain and ongoing inflammation.
IMPORTANT! This information is for educational purposes only and is NOT intended to replace the care or advice given by your physician. Boston Applied Biologics is not offering regenerative cell therapy or other regenerative therapies as a cure for any condition, disease, or injury. No statements or implied treatments on this website have been evaluated or approved by the FDA. This website contains no medical advice. All statements and opinions provided by this website are provided for educational and informational purposes only and we do not diagnose or treat via this website or via telephone. We do not claim that any applications, or potential applications, using autologous regenerative cells and other regenerative cells are approved by the FDA, or are even effective. We do not claim that these treatments work for any listed nor unlisted condition, intended or implied. Always seek the advice of your physician or other qualified health provider before starting any new treatment or with any questions you may have regarding a medical condition. For more information see our Medical Disclaimer.
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